Manager Biostatistics
Job Description
Why Patients Need You
Pfizer’s purpose is to deliver breakthroughs that change patients’ lives. Research and Development is at the heart of fulfilling Pfizer’s purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best in class medicines to patients around the world.
Pfizer Worldwide Medical and Safety colleagues play a key role in connecting evidenced based, medical decision support with colleagues and stakeholders to enable better health and treatment outcomes. Whether you are creating framework necessary to ensure our evidence is scientifically sound, providing unbiased, medically necessary expertise or investigating how to close gaps in data, our mission is simple. Empower healthcare decisions regarding the safe and appropriate use of medicines for patients.
What You Will Achieve
Pfizer's Non-Clinical Statistics is looking for a motivated statistician with a background in nonclinical statistics, strong consulting skills, and an interest in collaborating with research scientists in drug discovery and development. You will work closely with research scientists seeking to discover new medicines in a variety of therapeutic areas by supporting the design and analysis of preclinical experiments covering all aspects of drug discovery from disease target identification, pharmacology studies, animal model development, biomarker development and demonstration of proof of concept. The focus will be on both “platform” approaches (i.e. ensuring robust assay methods) as well as specific project approaches. You will have a genuine interest in understanding drug target biology in order to provide effective statistical consultation with biological scientists.
How You Will Achieve It
Collaborate with vaccine assay specialists to support vaccine clinical and diagnostic assay development, qualification, and validation
Collaborate with vaccine preclinical scientists to support vaccine preclinical and nonclinical development
Ensure statistical rigor and good scientific practices are followed, excellent statistical methods utilized, and documented in protocols, analysis plans and manuscripts
Provide statistical expertise to regulatory submissions and ensure quality and appropriateness of submission deliverables
Bring innovative statistical thinking and methods to maximize the value of aggregate clinical and preclinical data in support of scientific and vaccine development strategies
Serve as a core member of scientific teams responsible for determining strategy and delivering results in a timely and high quality manner
Where possible, standardize processes and methodologies, may include developing statistical tools to aid scientists in standardized analyses
Use statistical expertise to prepare both internal and external reports, presentations and manuscripts, with the aim to improve the quality of internal decision making and increase our influence on the external environment
Qualifications
Must-Have
Master degree in Statistics/Biostatistics
At least 3-5 years of pharmaceutical experience
Some pre-clinical and non-clinical experience is required
Must have strong technical competence, including statistical computing
Sound understanding of design of experiments, assay development, and statistical applications for preclinical research
Good knowledge of drug development regulations pertinent to statistical analysis
Works well in a team that has clear objectives and a functional working relationship between all members
Experience collaborating 1:1 with scientists and/or non-statisticians
Strong communication skills and the ability to work collaboratively with research scientists are essential
Demonstrated ability to create computational tools for data visualization
Statistical knowledge through coursework and/or demonstrated statistical application in general linear models, mixed models, non-linear models, experimental design, variance components, and quality control
Good computational skills in R and SAS
Demonstrated ability to work effectively as a part of a team. Strong communication skills and the ability to write technical reports
Nice-to-Have
PhD in Statistics/Biostatistics or relevant discipline
Assay validation experience, particularly clinical assays, is highly desired
Vaccine development experience is highly desired
PHYSICAL/MENTAL REQUIREMENTS
no physical requirements
ability to perform mathematical calculations and ability to perform complex data analysis
NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS
N/A
Relocation support available
Work Location Assignment:Hybrid
Relocation assistance may be available based on business needs and/or eligibility.
Sunshine Act
Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider’s name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.
EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.
